|  Zheng CJ, Li HQ, Ren SC, Xu CL, Rahman K, Qin LP, Sun YH. Our results have identified reliable HKGs for studies of normal human ovaries and those affected by OEA, OMA, OSPC, or PCOS, as well as combined studies of control subjects vs. each cancer or PCOS group. Programmed cell death factor 4 (PDCD4) is originally described as a tumor suppressor gene that exerts antineoplastic effects by promoting apoptosis and inhibiting tumor cell proliferation, invasion, and metastasis. The circRNA-miRNA axis functions in various diseases progression have been partially revealed in the past two decades. HHS Vitex negundo 161800 ± 36 143400 ± 23 5330 ± 16 200 ± 9 280 ± 10 120 ± 5 Potassium was higher in both plants but contained Adhatoda vasica 31190 ± 20.3 68070 ± 35 705 ± 8 64 ± 5 67 ± 6 41 ± 3 less Na. Cowpea seeds … -. The review includes 161 references on the genus Vitex, and comprises ethnopharmacology, morphology and microscopy, phytoconstituents, pharmacological reports, clinical studies, and toxicology of the prominent species of Vitex. Labdanes and megastigmanes from Vitex negundo var. Abstract Falko P. Drijfhout, E. David Morgan, in Comprehensive Natural Products II, 2010. These bioactive compounds exhibit anti-inflammatory, antioxidant, antidiabetic, anticancer, antimicrobial. Endometrial cancer is the most common gynecologic cancer and is predominantly endocrine-related. Vitex agnus-castus negundoides Kuntze. Advanced search can include the following: Vitex negundo and its medicinal value. 2014 Mar;93:31-8. doi: 10.1016/j.fitote.2013.12.006. It is especially useful in rheumatism, rheumatic swellings of the joints and in sprains. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. In women, AMH is a product of the small antral follicles in the ovaries and serves to function as an autocrine and paracrine regulator of follicular maturation. MicroRNA miR-760, which is characterized by tissue-specific, has been studied in several cancers. USA.gov. Ephrins are ligands of Eph receptors (Ephs); both of which are sorted into two classes, A and B. 2013 Dec 04;13:343 Life Cycle: Perennial Woody Recommended Propagation Strategy: Seed Country Or Region Of Origin: Asia, Africa Wildlife Value: Attracts butterflies. Vitex negundo (VN), commonly known as "chaste tree", is an ethnobotanically important plant with enormous medicinal properties. 2013 Oct;24(9):928-36 Roy SK, Bairwa K, Grover J, Srivastava A, Jachak SM. COVID-19 is an emerging, rapidly evolving situation. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using multivariable logistic regression for case–control associations and polytomous logistic regression for histotype-specific associations, all adjusted for po tential confounders. Epub 2013 Dec 22. Vitex cannabifolia Siebold & Zucc. 4.11.3.4.1 Pentacyclic triterpenes. It was observed that methanolic extract of Vitex negundo showed equal activity against both the bacteria with MIC value equal to 5mg/mL. Please enable it to take advantage of the complete set of features! Would you like email updates of new search results? Also known as chaste tree or chasteberry, it's often taken as a remedy for women's health problems. Fitoterapia. 2015 Jan 5;225:32-9 heterophylla. -, BMC Complement Altern Med. The phytochemical constituents of medicinal plants often function indi-vidually, additively or synergistically in improvement of health [31]. Vitex Negundo is a medicinal herb. Vitex arborea Desf. Vitex negundo (nirgundi, in Sanskrit and Hindi) is a deciduous shrub naturalized in many parts of the world. and on percentage of larval parasitism by Dinarmus vagabundus (Timberlake). In contrast, there is a growing body of evidence for a protective role of oral contraceptives. NCI CPTC Antibody Characterization Program, Phytomedicine. Also, there are ten types of EphAs (EphA1-10) and six types of EphBs (EphB1-6). Vitex Species: negundo Family: Lamiaceae Uses (Ethnobotany): Various medicinal uses of various parts of the plant. Keywords: Raji, R. (2013) Biological Activities, Chemical Constituents and Medicinal Value of Vitex negundo Linn. VN, reportedly, perturbs many cancer-signaling pathways involving p-p38, p-ERK1/2, and p-JNK in LPS-elicited cells, N-terminal kinase (JNK), COX-1 pathways, MAPK, NF-κB, tumor necrosis factor α (TNF-α), Akt, mTOR, vascular endothelial growth factor, hypoxia-inducible factor (HIF-1α). The Vitex negundo linn is another Indian plant, which have enormous traditional uses against various diseases. In our present work on the phytochemical and pharmacological properties of the leaves of vitex negundo was evidently support the long term Anti oxidant property, anti inflammatory, anti cancer and anti inflammatory activity of Vitex negundo. The ethanolic extract of leaves has been found safe as LD 50 dose (by oral route) of it was recorded in non-toxic dose range. Different species of Vitex vary in chemical composition, thus producing different phytochemicals. Casticin from Vitex species: a short review on its anticancer and anti-inflammatory properties. It is a feeling that is triggered in nervous system. The objective of this review is to summarize our knowledge about the contribution of vitamin D3 to physiological and pathological processes within the ovary. Vitex negundo (or nirgundi or nochi) is one of the herbs mentioned in the Ayurveda and it grows in the waste lands or commonly cultivated as a hedge plant. Pain is a feeling which may be sharp or dull, something that is unpleasant to mind and body. Lagundi is generally used for the treatment of coughs, asthma symptoms, and other respiratory problems. V. negundo and V. agnus castus are reported to contain the iridoid glucosides aucubin and agnuside [1]. The conventional method for propagation of V. negundo is through seeds or root suckers. Vitex negundo and its medicinal value. It is widely used in folk medicine, particularly in South and Southeast Asia. This may be mild, moderate or even severe. This is the first review presenting up-to-date information about the VN, its bioactive constituents and their mode of action. Clipboard, Search History, and several other advanced features are temporarily unavailable. Herbal Decoction Divya-Peedantak-Kwath Alleviates Allodynia and Hyperalgesia in Mice Model of Chemotherapy-Induced Peripheral Neuropathy via Modulation in Cytokine Response. Different species of Vitex vary in chemical composition, thus producing different phytochemicals. Epub 2018 Mar 6. It is used externally in the form of paste or oi and orally in the form of powder, leaf juice or water decoction.It treats diseases caused due to vitation of Vata and Kapha, Headache, Skin affections, Wounds, Swelling, Asthmatic Pains, male and female Sexual ailments and Reproductive problems. Front Pharmacol. Tuesday, 12 January 2010. Vitex negundo (VN), commonly known as "chaste tree", is an ethnobotanically important plant with enormous medicinal properties. Lagundi in Traditional and Folkloric Medicine Lagundi or Vitex negundo has been traditionally used as herbal medicine by Philippine and Indian folks. Vitex negundo and its medicinal value Author: Gill, Balraj Singh, Mehra, Richa, Navgeet,, Kumar, Sanjeev ... Vitex negundo (VN), commonly known as “chaste tree”, is an ethnobotanically important plant with enormous medicinal properties. Nirgundi Oil (Vitex negundo) - Benefits, Uses and Properties. Different reproductive factors such as younger age at menarche, late age at menopause, infertility, nulliparity, age of birth of the first child, and long-term use of unopposed estrogens during hormone replacement therapy have been associated with an increased risk of endometrial cancer. Commonly known in the Ilocos region as dangla, lagundi has been clinically tested to be effective in the treatment of colds, flu, bronchial asthma, chronic bronchitis, and pharyngitis. These bioactive compounds exhibit anti-inflammatory, antioxidant, antidiabetic, anticancer, antimicrobial. ann Fitoterapia. This site needs JavaScript to work properly. Different species of Vitex vary in chem …. Previous work on this plant reveals the presence of a variety of compounds from the leaves [1-11]. Balraj Singh Gill, Richa Mehra, undefined Navgeet, Sanjeev Kumar, Vitex negundo and its medicinal value, Molecular Biology Reports, 10.1007/s11033-018-4421-3, (2018). PMID: 32469224 [PubMed - as supplied by publisher], https://www.ncbi.nlm.nih.gov/pubmed/30311123?dopt=Abstract. Effect of Timing of Gonadotropin-Releasing Hormone Agonist Administration for Ovarian Protection in Patients with Breast Cancer. NLM medicinal plant for the preparation of various valuable medicines has caused drastic reduction of this important genetic resource in India. We performed a pooled analysis among parous participants from 12 case –controls studies comprising 6872 EOC patients and 9101 controls. Phytochemical and Pharmacological Profile of Vitex negundo. Kashyapiyakrishisukti recommends . Vitex negundo (VN), commonly known as “chaste tree”, is an ethnobotanically important plant with enormous medicinal properties. Trees and Herbs (with medicinal value) To treat disease and by using (Herbs)/herbal medicine. Authors: Gill BS, Mehra R, Navgeet, Kumar S back to its natural state of health [30]. is a large aromatic shrub distributed throughout India. Balraj Singh Gill, Richa Mehra, undefined Navgeet, Sanjeev Kumar, Vitex negundo and its medicinal value, Molecular Biology Reports, 10.1007/s11033-018-4421-3, (2018). However, little is known about the role of the circRNA-miRNA axis in PCOS progression. It also produces pain relief similar to aspirin and morphine in animal tests. J Integr Med. It is one of the ten herbal medicines endorsed by the Philippine Department of Health as an effective herbal medicine with proven therapeutic value. -, Chem Biol Interact. There are five types of ephrin-As (ephrin-A1-5) and three types of ephrin-Bs (ephrin-B1-3). Natural products are rich in several potent bioactive compounds, targeting complex network of proteins involved in various diseases. Mol Biol Rep. 2019 Jun;46(3):3545-3555. doi: 10.1007/s11033-019-04743-5. 2020 Oct 30;11:566490. doi: 10.3389/fphar.2020.566490. Zheng CJ, Zhang XW, Han T, Jiang YP, Tang JY, Brömme D, Qin LP. Epub 2015 Jan 30. It is a muscle relaxant and pain relieving herb. Different species of Vitex vary in chemical composition, thus producing different phytochemicals. Biologically synthesized green silver nano-particles from leaf extract of Vitex negundo L. induce growth-inhibitory effect on human colon cancer cell line HCT15 136. Clarification of their roles in the female reproductive system is crucial to understanding the physiology and pathology of this syste... Adu-Gyamfi EA, Czika A, Liu TH, Gorleku PN, Fondjo LA, Djankpa FT, Ding YB, Wang YX. Offspring sex and risk of epithelial ovarian cancer: a multinational pooled analysis of 12 case –control studies. INTRODUCTION Vitex negundo is well known for its medicinal value [1]. Anti-inflammatory and anti-osteoporotic lignans from Vitex negundo seeds. Vitex agnus-castus negundo (L.) Kuntze. Abstract VN is typically known for its role in the modulation of cellular events like apoptosis, cell cycle, motility of sperms, polycystic ovary disease, and menstrual cycle. The word pain comes from the Latin name - Poena, means a fine or penalty. 2018 May;16(3):147-152. doi: 10.1016/j.joim.2018.03.001. Marine macroalga Caulerpa: role of its metabolites in modulating cancer signaling. Universal Journal of Pharmacy, 2, 42-46. It;'s main health benefit is to ease respiratory complaints.  |  Mol Biol Rep. 2018 Oct 11;: Authors: Gill BS, Mehra R, Navgeet, Kumar S Abstract Natural products are rich in several potent bioactive compounds, targeting complex network of proteins involved in various diseases. Epub 2019 Jul 11. 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